Course Code	Semester	Course Name	LE/RC/LA	Course Type	Language of Instruction	ECTS
HEM3010		Genetic	2/0/0	DE	Turkish	3

Course Goals	Within the scope of the course, the structures of molecules such as DNA, nucleic acids and chromosomes will be examined, and information will be learned about the organization of these functional structures in cell divisions. It is aimed to have information about central dogma (transcription, translation) molecular genetics, to have information about recombinant DNA technology, to have knowledge about mutation-polymorphisms. It is aimed to give examples from the mechanisms of cancer and various genetic diseases caused by mutations. With the help of RNA biology, genetic testing and counseling, it is aimed that students have information on the latest current issues in genetics.
Prerequisite(s)	-
Corequisite(s)	-
Special Requisite(s)	-
Instructor(s)	Assist. Prof. Dr. Alp Ayan
Course Assistant(s)
Schedule	-
Office Hour(s)	-
Teaching Methods and Techniques	-Oral expression, question - answer method, discussion.
Principle Sources	-
Other Sources	-

Course Schedules
Week	Contents	Learning Methods
1. Week	Nucleic acids, DNA, chromosome definitions	Verbal lecture, discussion, video demonstration
2. Week	Mitosis and meiosis, DNA replication and cell cycle	Verbal lecture, discussion, video demonstration
3. Week	Mendelian inheritance, genotype and phenotype	Verbal lecture, discussion, video demonstration
4. Week	Molecular genetics of the central dogma	Verbal lecture, discussion, video demonstration
5. Week	Molecular genetics of the central dogma	Verbal lecture, discussion, video demonstration
6. Week	Recombinant DNA technology	Verbal lecture, discussion, video demonstration
7. Week	Mutation, DNA sequence variation: polymorphism	Verbal lecture, discussion, video demonstration
8. Week	Regulation of cell number: normal and cancer cells	Verbal lecture, discussion, video demonstration
9. Week	Genetic diseases: Cystic Fibrosis, Thalassemia, Marfan syndrome, Fragile X syndrome, Turner, Klinefelter	Verbal lecture, discussion, video demonstration
10. Week	Genetic diseases: Alzheimer's disease, Parkinson, ALS, Down Syndrome, Huntington, SMA, Tay-Sachs	Verbal lecture, discussion, video demonstration
11. Week	Genetic tests and genetic counseling	Verbal lecture, discussion, video demonstration
12. Week	RNA'S biology	Verbal lecture, discussion, video demonstration
13. Week	Recent advances in Molecular Biology and Genetics: gene therapy, CRISPR and genome editing,	Verbal lecture, discussion, video demonstration
14. Week	Recent advances in Molecular Biology and Genetics: RNA interference	Verbal lecture, discussion, video demonstration
15. Week	Final exam
16. Week
17. Week

Assessments
Evaluation tools	Quantity	Weight(%)
Midterm(s)	1	10
Homework / Term Projects / Presentations	1	40
Attendance / Participation	1	10
Final Exam	1	40

Program Outcomes PO-1 Has the current theoretical knowledge required by the nursing profession. PO-2 Has the practical skills to meet the health needs of individuals, families, groups and society with a holistic and humanistic approach. PO-3 Applies quality and evidence-based nursing care process while meeting the health needs of individual, family, group and society. PO-4 It considers ethical principles in nursing care, education, management and research. PO-5 Follows nursing laws and regulations and acts appropriately. PO-6 Uses effective communication skills. PO-7 It provides health education and counseling services to individuals, families, groups and communities. PO-8 As an active member of the healthcare team, it fulfills its roles and functions in intra-disciplinary and interdisciplinary cooperation. PO-9 It shows an empathic approach in a sensitive way to all kinds of changes that may affect the health of the individual, family, group and society. PO-10 It uses lifelong learning, problem solving and critical thinking skills. PO-11 Follows up-to-date care technologies in line with the health needs of the society and reflects them on nursing practices. PO-12 While practicing the profession, she becomes a role model for her/his colleagues. PO-13 It protects the core professional values it has acquired. PO-14 Uses professional autonomy in health related decisions.

Learning Outcomes LO-1 Identifying DNA, chromosomes and nucleic acids, understanding how these structures are organized in DNA replication and cell division LO-2 Knowing about Mendelian inheritance LO-3 To be able to define the genetics of central dogma, recombinant DNA technology and mutation concepts LO-4 Learning the genetics of cancer, cystic fibrosis, thalassemia, Marfan syndrome, Fragile X syndrome, Turner, Klinefelter, Alzheimer's disease, Parkinson, ALS, Down Syndrome, Huntington, SMA, Tay-Sachs diseases LO-5 To have knowledge about genetic tests, genetic counseling, RNA biology LO-6 To have up-to-date knowledge of molecular biology and gene therapy in genetics, CRISPR and genome editing, RNA interference technologies

Course Assessment Matrix:

PO 1

PO 2

PO 3

PO 4

PO 5

PO 6

PO 7

PO 8

PO 9

PO 10

PO 11

PO 12

PO 13

PO 14

LO 1

LO 2

LO 3

LO 4

LO 5

LO 6