The aim of this course is to provide basic knowledge to the students on general biophysics and molecular biophysics and provide the basis molecular biology and genetic sciences.
Prerequisite(s)
-
Corequisite(s)
-
Special Requisite(s)
attendance
Instructor(s)
Professor Sevim Akyüz
Course Assistant(s)
Schedule
Wednesday, 13.00-16.00; B1-4 lecture room
Office Hour(s)
Tuesday 12.00-13.00; AK 3A-16, Prof. Dr. Sevim Akyuz's office.
Teaching Methods and Techniques
Presentation, discussion, demonstrations by using simulations programs
Principle Sources
-Biophysics lecture notes, Prof. Dr. Sevim Akyüz,
-Biophysics, Gürbüz Çelebi, Çağlayan publications,
Other Sources
--Biophysics, Ferit Pehlivan, Ankara, 1997
-Introduction to Biophysics,Doç. Dr. Osman Ziya Sayhan,Evrim Yayınevi ISBN 978-975-503-201-5.
Course Schedules
Week
Contents
Learning Methods
1. Week
Introduction to biophysics, basic concepts, basic structure of living systems, quantum theory of atomic and molecular structures, chemical bonds
Presentation, discussion, question and answer method
2. Week
Cell structure, water molecule, physical and chemical properties of water,biomolecules
Presentation, discussion, question and answer method
3. Week
Oxygens-carrying proteins, structural and functional relations of biomolecules on the example of hemoglobin, myoglobin
Presentation, discussion, question and answer method
4. Week
Definition of radioactivity, radiation biophysics, biological effects of radiation, properties of radioisotopes and their applications in medicine, production of X-rays and medical applications of X-rays
Presentation, discussion, question and answer method
5. Week
Cellular respiration, aerobic formation of ATP in mitochondria. Biological function. Chemical function, mechanic function, osmotic function (biosynthesis muscle contraction, active messengers). Transfer of molecules from membrane by bioenergetics .
Presentation, discussion, question and answer method
6. Week
Membrane potentials, electrically equivalent circuits and models. Inducible cells action potentials, bioelectrical potentials. Molecular mechanisn of mechanical function (muscle contraction)
Presentation, discussion, question and answer method
7. Week
Cellular respriration, aerobic formation of ATP in mitochondria, biological work, chemical work, osmotic work
Presentation, discussion, question and answer method
Presentation, discussion, question and answer method
9. Week
Applications to membrane electrically equivalent circuits
Presentation, discussion, question and answer method
10. Week
Mechanical work,myosin flament, actin flament, muscle contraction energy source
Presentation, discussion, question and answer method
11. Week
Biophysics of the auditory organ,refrection and refrection of the sound waves,ear anatomy Theories of hearing
Presentation, discussion, question and answer method
12. Week
Medical imaging methods;X-ray imaging methods, Nuclear magnetic resonance
Presentation, discussion, question and answer method
13. Week
Other medical imaging methods
Presentation, discussion, question and answer method
14. Week
Pozitron emission Tomography and advantages
Presentation, discussion, question and answer method
15. Week
Final exam
16. Week
Final exam
17. Week
Fianl exam
Assessments
Evaluation tools
Quantity
Weight(%)
Midterm(s)
1
40
Homework / Term Projects / Presentations
1
5
Attendance
1
5
Final Exam
1
50
Program Outcomes
PO-1
To apply all knowledge about basic sciences such as mathematics, physics, chemistry and biology to all problems in molecular biology and genetics
PO-2
To be able to identify, model and produce solutions against to problems related to molecular biology and genetics
PO-3
To start a procedure, proceed and finalize about determined problem by using analytical techniques
PO-4
To be able to understand all knowledge about living organisms which is main subject of molecular biology and genetics
PO-5
To contribute scientific research and development and add further information
PO-6
To be able to analyze data, design an experiment and proceed and annoate the results
PO-7
To be able to use current techniques and analysis methods in molecular biology and genetics
PO-8
To be able to be a part of a team in disciplinary or multidisciplinary, national or international public problems focused projects and use at least one foreign language for vocational purposes
PO-9
To be able to behave individually, take initiative and creativity skills
PO-10
To communicate briefly and clear using oral or written presentation skills to present individual working performance and independent decisions
PO-11
To carry responsibility to vocational and ethical issues
PO-12
To be aware about quality assessment
PO-13
To adopt in principle the importance of life-learning subject and graduate self-development by following new literature about field and apply current knowledge
Learning Outcomes
LO-1
Learn how to apply the laws of physics and physical methods to biological systems
LO-2
Gain knowledge on general biophysics and molecular biophysics
LO-3
Gain knowledge on radiation biophysics, biological effects of radiation, radioisotope properties and their applications.
LO-4
Gain knowledge on bioenergetics-energy flow through living systems and general communication systems-cybernetics.
LO-5
Learn cellular respiration and gain knowledge on respiratory biophysics, biopysics of vision, auditory biopysics
