Course Code	Semester	Course Name	LE/RC/LA	Course Type	Language of Instruction	ECTS
MBG5002	5	Molecular Genetics I	3/0/0	CC	Turkish	6

Course Goals	Learning the basic properties of nucleic acid molecules shaping the organism's genetic information, understanding the chromosomal organization and packaging in prokaryotic and eukaryotic organisms, understanding the mechanism of DNA replication, learning the transcription and translation in gene expression in prokaryotic and eukaryotic organisms with comparison between the organisms, learning the basics of genetic code
Prerequisite(s)	-
Corequisite(s)	-
Special Requisite(s)	-
Instructor(s)	Professor Özgür Çakır
Course Assistant(s)	-
Schedule	-
Office Hour(s)	Weekdays, Molecular Biology and Genetics Department, M-1-03
Teaching Methods and Techniques	- Power point presentations - Lecture - Discussion - Independent study - Animation and videos - Internet reserach
Principle Sources	- Watson, Baker, Bell, Gann, Levine, Losick, Molecular Biology of the Gene, 6th Edition, Pearson Publications, 2008 (ISBN: 978-0805395921) - Turner, McLennan, Bates, White, Moleküler Biyoloji, Önemli Notlar, Çeviri editörü Prof.Dr. Muhsin Konuk,  Nobel Kitapevi, 2004 (ISBN: 9789755915968) - Russell, iGenetics : A Molecular Approach, 3rd Edition, Pearson Publications, 2009 (ISBN: 978-0-321-56976-9) - Eliot, Ladomery, Molecular Biology of RNA, Oxford Publications, 2011 (ISBN: 978-0-19-928837-3)
Other Sources	- http://www.dnalc.org/resources/animations/ - http://highered.mcgraw-hill.com/sites/0072835125/student_view0/animations.html# - http://www.dnatube.com/ - http://www.web-books.com/BookInfo.php?BookID=1 - http://learn.genetics.utah.edu/

Course Schedules
Week	Contents	Learning Methods
1. Week	Introduction to molecular genetics: genomics, transcriptomics, proteomics	Oral presentation
2. Week	Working with DNA	Oral presentation
3. Week	Genome mapping	Oral presentation
4. Week	Genom sekanslama	Oral presentation
5. Week	Genome annotation	Oral presentation
6. Week	Gene function	Oral presentation
7. Week	Midterm I	Oral presentation
8. Week	Bakteriyal and viral genome	Oral presentation
9. Week	Eukaryotic nuclear and organelle genome	Oral presentation
10. Week	DNA replication	Oral presentation
11. Week	Mutation and DNA repair system	Oral presentation
12. Week	Recombination mechanisms: Non-Homolog recombination; transposon and sites-specific recombination mechanisms	Oral presentation
13. Week	Recombination mechanisms: Homolog recombination	Oral presentation
14. Week	Genom editing mechanisms	Oral presentation
15. Week	Final exam
16. Week	Final exam
17. Week	Final exam

Assessments
Evaluation tools	Quantity	Weight(%)
Midterm(s)	1	20
Homework / Term Projects / Presentations	2	20
Attendance	1	10
Final Exam	1	50

Program Outcomes PO-1 To apply all knowledge about basic sciences such as mathematics, physics, chemistry and biology to all problems in molecular biology and genetics PO-2 To be able to identify, model and produce solutions against to problems related to molecular biology and genetics PO-3 To start a procedure, proceed and finalize about determined problem by using analytical techniques PO-4 To be able to understand all knowledge about living organisms which is main subject of molecular biology and genetics PO-5 To contribute scientific research and development and add further information PO-6 To be able to analyze data, design an experiment and proceed and annoate the results PO-7 To be able to use current techniques and analysis methods in molecular biology and genetics PO-8 To be able to be a part of a team in disciplinary or multidisciplinary, national or international public problems focused projects and use at least one foreign language for vocational purposes PO-9 To be able to behave individually, take initiative and creativity skills PO-10 To communicate briefly and clear using oral or written presentation skills to present individual working performance and independent decisions PO-11 To carry responsibility to vocational and ethical issues PO-12 To be aware about quality assessment PO-13 To adopt in principle the importance of life-learning subject and graduate self-development by following new literature about field and apply current knowledge

Learning Outcomes LO-1 Learning the properties of nucleic acids; the most important molecule in molecular biology and genetics. LO-2 Understanding the chromosomal organisation in prokaryotic and eukaryotic organisms and learning the basics of DNA replication with respect to organism. LO-3 Understanding the levels of gene expression in prokaryotic and eukaryotic organisms, gaining the ability to comprehend and compare the similarities and differences during transcription and translation in these organisms. LO-4 Gaining the ability to comprehend a molecular mechanism from a figure and to draw a figure for a given molecular mechanism. LO-5 Gaining the ability to draw conclusions for a given problem and to discuss the results based on scientific background.

Course Assessment Matrix:

PO 1

PO 2

PO 3

PO 4

PO 5

PO 6

PO 7

PO 8

PO 9

PO 10

PO 11

PO 12

PO 13

LO 1

LO 2

LO 3

LO 4

LO 5