To learn the basic properties of the ionized radiation, to apprehend the effects of radiation on biomaterials, cell organels and cell level and to get knowledge on the genetic mechanisms of the response of cellular radiation
Prerequisite(s)
Course Code Course Name…
Corequisite(s)
Course Code Course Name…
Special Requisite(s)
The minimum qualifications that are expected from the students who want to attend the course.(Examples: Foreign language level, attendance, known theoretical pre-qualifications, etc.)
Friday, 10:00-12:00, Prof. Dr. Atilla Özalpan Room
Teaching Methods and Techniques
-ppt presentetion and discussion
Principle Sources
-1- Özalpan A. Temel Radyobiyoloji, Haliç Üniversitesi Yayınları, 2001.
2- Hall EJ. Radiobiology for the Radiologist, Lippincott Williams & Wilkins, Philadelphia, 2006.
3- Nias AHW. An İntroduction to Radiobiology, John Wiley and Sons Ltd, 1998.
Other Sources
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Course Schedules
Week
Contents
Learning Methods
1. Week
Basic definitions and terms
ppt presentetion and discussion
2. Week
General properties of ionized radiations
ppt presentetion and discussion
3. Week
Absorption of radition energy
ppt presentetion and discussion
4. Week
Distribution of the radition energy, LET and RBE terms
ppt presentetion and discussion
5. Week
The effects of radition on nucleic acids, enzymes and proteins
ppt presentetion and discussion
6. Week
The effects of radiation on chromosomes
ppt presentetion and discussion
7. Week
The growth kinetics of cell populations
ppt presentetion and discussion
8. Week
Dividing cells and cell survival terms
ppt presentetion and discussion
9. Week
The methods used for getting the cell survival curves
ppt presentetion and discussion
10. Week
Cell survival curves and cell death models
ppt presentetion and discussion
11. Week
Cell synchronization and synchronized culture properties
ppt presentetion and discussion
12. Week
The different radiation sensitivity of cells that are in different phase of cell cycle
ppt presentetion and discussion
13. Week
Genetic control of the cellular radiation response
ppt presentetion and discussion
14. Week
Presentetions
Student presentation
15. Week
Final week
16. Week
Final week
17. Week
Final week
Assessments
Evaluation tools
Quantity
Weight(%)
Midterm(s)
1
30
Homework / Term Projects / Presentations
1
10
Attendance
1
5
Final Exam
1
55
Program Outcomes
PO-1
To apply all knowledge about basic sciences such as mathematics, physics, chemistry and biology to all problems in molecular biology and genetics
PO-2
To be able to identify, model and produce solutions against to problems related to molecular biology and genetics
PO-3
To start a procedure, proceed and finalize about determined problem by using analytical techniques
PO-4
To be able to understand all knowledge about living organisms which is main subject of molecular biology and genetics
PO-5
To contribute scientific research and development and add further information
PO-6
To be able to analyze data, design an experiment and proceed and annoate the results
PO-7
To be able to use current techniques and analysis methods in molecular biology and genetics
PO-8
To be able to be a part of a team in disciplinary or multidisciplinary, national or international public problems focused projects and use at least one foreign language for vocational purposes
PO-9
To be able to behave individually, take initiative and creativity skills
PO-10
To communicate briefly and clear using oral or written presentation skills to present individual working performance and independent decisions
PO-11
To carry responsibility to vocational and ethical issues
PO-12
To be aware about quality assessment
PO-13
To adopt in principle the importance of life-learning subject and graduate self-development by following new literature about field and apply current knowledge
Learning Outcomes
LO-1
To learn the properties of radiation and the pathways of the radiation energy transfer to substance
LO-2
To learn the structural damage that the radition effect on nucleic acids and proteins and breaks on the chromosomes and their results
LO-3
To learn the growth kinetics of cell populations, the term of cell survival and cell death models
LO-4
To learn the different radiation sensitivity of cells that are in different phase of cell cycle and to learn the reasons
LO-5
To learn the genetic control phases of cellular radiation sensitivity, DNA damage, repair mechanisms
