The aim of this lecture is to show the effects of molecular biology on evolutionary biology and the supplements to improve this area. During this lecture, it is intended to teach to the students that the terms of evolution and molecular evolution in the base of using molecular biology techniques in evolutionary biology and the researches on evolution models and comparisons.
Prerequisite(s)
-
Corequisite(s)
-
Special Requisite(s)
-
Instructor(s)
Assist. Prof. Dr. Alp Ayan
Course Assistant(s)
Schedule
Not defined
Office Hour(s)
Every day, Ataköy Campus, MOBIGEN
Teaching Methods and Techniques
-Lecturer based presentations, student based presentations
Principle Sources
--Graur, D. Li, W-H. fundamentals of molecular evolution. Sinauer Associates, 2000.
Evolutionary Genetics, Smith, J.M. Oxford University Press, 2004.
Page R., D.M. Holmes,E.C. Holmes. Molecular Evolution: A Phylogenetic Approach, Wiley-Blackwell Publishing Ltd, 1998.
Futuyma, D.J. Evrim, Çeviri ed. Kence, A. Bozcuk, A.N. Palme Yayıncılık 2008.
Other Sources
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Course Schedules
Week
Contents
Learning Methods
1. Week
What is evolution and molecular evolution?. Darwin and the principles of evolution.
Oral presentation
2. Week
Classification and phylogeny, molecular clocks and gene trees
Oral presentation
3. Week
Molecular phylogeny
Oral presentation
4. Week
The source of hereditary diversities, genes and genomes, gene mutations
Oral presentation
5. Week
Mutation as a spontaneous formation, karyotype changes
Oral presentation
6. Week
The basic rules of diversity in community, genetic varieties in natural communities, polymorphism, varities of proteins and DNA
Oral presentation
7. Week
Midterm Exam
Exam
8. Week
Genetic drift and evolution, Neutral allel theory in molecular evolution, gene movement and genetic drfit
Oral presentation
9. Week
Natural selection and adaptation
Oral presentation
10. Week
The genetic rules and molecular traces of natural selection
Oral presentation
11. Week
The evolution of genes and proteins
Oral presentation
12. Week
Genom diversity and evolution, repeated sequences and moving heritable elements
Oral presentation
13. Week
Discovery of new genes, duplication, phylogenetic and adaptive diversify in gene families
Oral presentation
14. Week
The supplements of molecular evolution on health, agriculture, natural sources and environment
Oral presentation
15. Week
16. Week
17. Week
Assessments
Evaluation tools
Quantity
Weight(%)
Midterm(s)
1
40
Homework / Term Projects / Presentations
1
20
Attendance
1
0
Final Exam
1
40
Program Outcomes
PO-1
To apply all knowledge about basic sciences such as mathematics, physics, chemistry and biology to all problems in molecular biology and genetics
PO-2
To be able to identify, model and produce solutions against to problems related to molecular biology and genetics
PO-3
To start a procedure, proceed and finalize about determined problem by using analytical techniques
PO-4
To be able to understand all knowledge about living organisms which is main subject of molecular biology and genetics
PO-5
To contribute scientific research and development and add further information
PO-6
To be able to analyze data, design an experiment and proceed and annoate the results
PO-7
To be able to use current techniques and analysis methods in molecular biology and genetics
PO-8
To be able to be a part of a team in disciplinary or multidisciplinary, national or international public problems focused projects and use at least one foreign language for vocational purposes
PO-9
To be able to behave individually, take initiative and creativity skills
PO-10
To communicate briefly and clear using oral or written presentation skills to present individual working performance and independent decisions
PO-11
To carry responsibility to vocational and ethical issues
PO-12
To be aware about quality assessment
PO-13
To adopt in principle the importance of life-learning subject and graduate self-development by following new literature about field and apply current knowledge
Learning Outcomes
LO-1
Using molecular biology techniques in evolutionary biology
LO-2
Understanding the evolution of genes and proteins and genetic varieties in natural communities
LO-3
The importance of gene families and phylogenetic analyses
LO-4
Learning molecular evolution models
LO-5
To show the comparisons between species and to use them in solving genetic problems.
