Undergraduate
Faculty of Science and Letters
Molecular Biology And Genetics
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Cell Molecular Biology II

Course CodeSemester Course Name LE/RC/LA Course Type Language of Instruction ECTS
MBG8001 8 Cell Molecular Biology II 3/0/0 CC Turkish 5
Course Goals
To give knowlegde structural mechanisms such as cell skeleton and cell adhesion,to teach important cellular mechanisms such as  cell division, cell cycle, apoptosis and fertilisation. Therefore to provide to students to design their own research during their Master of Science degree and upper levels
Prerequisite(s) -
Corequisite(s) -
Special Requisite(s) -
Instructor(s) Professor Çimen Atak
Course Assistant(s) -
Schedule Monday 14.00-16.00 Friday 11.00-12.00
Office Hour(s) Everyday
Teaching Methods and Techniques ppt presentations, videos and animations
Principle Sources

Molecular Cell Biology. (Eighth Edition) Lodish et al. (2016). ISBN-13: 978-1-4641-8339-3, ISBN-10: 1-4641-8339-2 © 2016, 2013, 2008, 2004 by W. H. Freeman and Company. New York www.macmillanhighered.com

Molecular biology of the cell /Sixth edition. (2015). Alberts,B. At al.. Preceded by Molecular biology of the cell / Bruce Alberts ... [et al.]. 5th ed. c2008. ISBN 978-0-8153-4432-2, ISBN 978-0-8153-4464-3. Published by Garland Science, Taylor & Francis Group, United States of America

Other Sources -
Course Schedules
Week Contents Learning Methods
1. Week Cell Skeleton filaments, microtubules, actin and intermediate filaments oral presentation
2. Week Importance of the nucleation, microtubule elongation, actin polymerization oral presentation
3. Week Chemicals affecting filament elongation, actin nucleation, elongation and filament organisation oral presentation
4. Week focal adhesion and adhesion belts, desmosoms, 1st quiz oral presentation
5. Week Molecular motors, microtubule motor proteins, molecular mechanisms of cell movement oral presentation
6. Week Cell cycle, cell cycle control systems, molecular mechanism of the cell cycle in yeast, growth factors and cell proliferation, apoptosis 2nd quiz oral presentation
7. Week Mechanism of the cell division, spindle formation, molecular characteristics of tanaphase, telophase, cytokinesis oral presentation
8. Week Cell adhesion types and their molecular fuctions, 1st midterm exam oral presentation
9. Week Gap junctions, plasmodesma, cell-cell adhesion, cadherins, selectins, 3rd quiz oral presentation
10. Week Extracellular matrix elements and their characteristics, GAGs, hyluronan and proteoglicans oral presentation
11. Week Collagen, fibril organisation, elastin, 4th quiz oral presentation
12. Week Molecular structure and function of the fibronectin, extracellularmatrix glicoproteins, 2nd midterm exam oral presentation
13. Week Basal lamina, structure of the integrins and their types oral presentation
14. Week Germ cells and fertilisation oral presentation
15. Week
16. Week
17. Week
Assessments
Evaluation tools Quantity Weight(%)
Midterm(s) 1 20
Homework / Term Projects / Presentations 1 30
Final Exam 1 50


Program Outcomes
PO-1To apply all knowledge about basic sciences such as mathematics, physics, chemistry and biology to all problems in molecular biology and genetics
PO-2To be able to identify, model and produce solutions against to problems related to molecular biology and genetics
PO-3To start a procedure, proceed and finalize about determined problem by using analytical techniques
PO-4To be able to understand all knowledge about living organisms which is main subject of molecular biology and genetics
PO-5To contribute scientific research and development and add further information
PO-6To be able to analyze data, design an experiment and proceed and annoate the results
PO-7To be able to use current techniques and analysis methods in molecular biology and genetics
PO-8To be able to be a part of a team in disciplinary or multidisciplinary, national or international public problems focused projects and use at least one foreign language for vocational purposes
PO-9To be able to behave individually, take initiative and creativity skills
PO-10To communicate briefly and clear using oral or written presentation skills to present individual working performance and independent decisions
PO-11To carry responsibility to vocational and ethical issues
PO-12To be aware about quality assessment
PO-13To adopt in principle the importance of life-learning subject and graduate self-development by following new literature about field and apply current knowledge
Learning Outcomes
LO-1To learn molecular structures, mechanisms and molecular functions of cell skeleton elements
LO-2To learn molecular mechanisms of the cell cycle related with cell viability and apoptosis
LO-3To learn the molecular mechanism of the cell division mechanism
LO-4To learn cell adhesion types, extracellular matrix elements and their relations
LO-5To learn germ cells structures and mechanisms druing cell division
Course Assessment Matrix:
Program Outcomes - Learning Outcomes Matrix
 PO 1PO 2PO 3PO 4PO 5PO 6PO 7PO 8PO 9PO 10PO 11PO 12PO 13
LO 1
LO 2
LO 3
LO 4
LO 5