It is aimed to teach at first to describe the cell signalling mechanism, signal types and different signalling pathways. Then to teach the signalling pathways in details at molecular level and to focuse on signalling mechanism demeges and human diseases relations. This course is going to provide a detailed understanding cell signalling mechanisms and relations with different cancers, therefore students are going to be able to design and command their researches at undergradute and graduate levels.
Prerequisite(s)
Course Code Course Name…
Corequisite(s)
Course Code Course Name…
Special Requisite(s)
-
Instructor(s)
Assist. Prof. Dr. Özge Rencüzoğulları
Course Assistant(s)
-
Schedule
Atakoy Campus, MOBIGEN Building
Office Hour(s)
Prof. Dr. Narcin Palavan-Unsal, Everyday, MOBIGEN Building
Teaching Methods and Techniques
-Lectures, ppt presentations, videos and animations
Principle Sources
-. Hancock, Cell Signalling, Oxford University Press, 2005.
- JW Wang and R. Casero, Polyamine Cell Signalling.Physiology, Pharmacology and Cancer Research. Humana Press, 2006.
- D. Batien et al. Signal Transduction, Elsevier Academic Press, 2005.
- Farklı web sayfaları
Other Sources
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Course Schedules
Week
Contents
Learning Methods
1. Week
Molecular basis of cell signalling mechanisms
Lecture, ppt presentations, animations
2. Week
Different cell signalling pathways and their coordination
Lecture, ppt presentations and animations
3. Week
Extracellular signals, hormones and cytokines
Lectures, ppt presentations, animations
4. Week
Growth factors
Lectures, ppt presentations and animations
5. Week
Neurotransmitters, ATPases, feromones
Lectures, ppt presentations and animations
6. Week
Detection of exstracellular signals
Lectures, ppt presentations and animations
7. Week
The roles of receptors,receptor types, binding of ligands to receptors, protein phosphorylation
Lectures, ppt presentations, animations
8. Week
Kinases, phosphatases, cyclic nucleotides
Lectures, ppt presentations, animations,
9. Week
Cyclases and G proteins
Lectures, ppt presentations, animations
10. Week
Inositol phosphate metabolism
Lectures, ppt presentations, animations
11. Week
The roles of membrane lipids
Lectures, ppt presentations, animations
12. Week
Intracellular calcium
Lectures, ppt presentations, animations
13. Week
Reactive oxygen species, reactive nitrogen species
Lectures, ppt presentations, animations
14. Week
Insulin and signal cascade
Lectures, ppt presentations, animations
15. Week
Final
16. Week
Final
17. Week
Final
Assessments
Evaluation tools
Quantity
Weight(%)
Program Outcomes
PO-1
To be able to determine the field related problems and analysis them to find the solutions as a specialist by using the knowledge coming from undergraduate level.
PO-2
To be able to develop and apply research strategies, which depend on the new technological achievements, for novel studies about molecular cell biology, plant biotechnology and molecular genetics fields on the basis of undergraduate qualifications.
PO-3
To be able to discuss field related subjects by using at least one foreign language.
PO-4
To be sensitive against public problems and be able to create solutions to these problems by synthesis of knowledge coming from other disciplines with the abilities and knowledge of the related field
PO-5
To be able to take independent decision in the frame of specialized knowledge and scientific approach about field and lead/proceed a project by using creativity skills.
PO-6
To be able to decide independently during solving the problem and contribute the group labor in harmony.
PO-7
To be able to present information which is supported by quantitative and qualitative data to groups in/outside of the field by written, oral and visually.
PO-8
To consider to behave properly in human rights and scientific ethics at research.
PO-9
To be able to use informatics and communication skills according required level for area.
PO-10
To obtain required quality about field in order to maintain higher academic degree
Learning Outcomes
LO-1
To learn the molecular basis of signal transductions in cells
LO-2
To learn cell ligand and receptor relations in detail
LO-3
To learn the different cell signalling pathways
LO-4
To learn the defects in different cell signalling pathways
LO-5
To learn the cell signalling pathways, their defects and different cancer relations at molecular level
