It is aimed to teach stem cells and their types, isolation techniques, clinical applications and ethical aspects and regulations. In addition, the students will have detailed information about stem cells and their application in molecular biology and genetics.
Oral presentation, case study, analysis, discussion
Principle Sources
Kök hücre biyolojisi ve klinik uygulamalar. TÜBA yayınları
http://www.tuba.gov.tr/tr/kok-hucre-yayinlar/1511-kok-hucre-biyolojisi-ve-klinik-uygulamalar.html
Kök hücre araştırmalarında güncel kavramlar, TÜBA yayınları
http://www.tuba.gov.tr/tr/kok-hucre-yayinlar/1512-kok-hucre-aratirmalarinda-guncel-kavramlar.html
Essentials of stem cell biology, Robert Lanza et al. (2nd edition) Academic press
Other Sources
Given keywords are going to be searched in electronic databases
www.pubmed.com
www.sciencedirect.com
Course Schedules
Week
Contents
Learning Methods
1. Week
What is stem cell biology? Targets and contents, stem cell types, classification of stem cells due pluripotential capacity
Lecture, discussion
2. Week
What is embryonic stem cells? Determination techniques and their application
Lecture, discussion
3. Week
What is adult stem cell? The comparison between embronic and adult stem cells for their similarities and dissimilarities
Lecture, discussion case study
4. Week
Haemotopoetic stem cells, their application fields, cord blood banking
Lecture, discussion case study
5. Week
Mesenchimal stem cells, molecular targets for their characterization, application fields
Lecture, discussion case study
6. Week
Isolation of stem cells and clinical applications
Lecture, discussion case study
7. Week
Mid-term, chosen of take home study subjects on stem cells in clinics
Analysis and synthesis, assay writing
8. Week
Stem cells in clinic tissue engineering
Lecture, discussion
9. Week
The debate on stem cells and gene therapy
Lecture, discussion case study
10. Week
The debate on stem cell applications in the world, ethical and regulations in law
Lecture, discussion case study
11. Week
Current topics in stem cell biology: The utilization of iPS cells
Lecture, discussion case study
12. Week
Current topics in stem cell biology: Characterization of mesenchimal cells by fluorosence techniiques
Lecture, discussion case study
13. Week
Non-invasive stem cell sources (adipocytes etc.)
Lecture, discussion case study
14. Week
Future aspects of stem cells and their study field
Lecture, discussion case study
15. Week
Final exam week: Take home study evaluation
Synthesis, analysis, research, assay writing
16. Week
Final exam week: Final examination
Synthesis, analysis
17. Week
Final exam week
Synthesis, analysis
Assessments
Evaluation tools
Quantity
Weight(%)
Midterm(s)
1
25
Homework / Term Projects / Presentations
1
25
Literature review
4
20
Final Exam
1
30
Program Outcomes
PO-1
To apply all knowledge about basic sciences such as mathematics, physics, chemistry and biology to all problems in molecular biology and genetics
PO-2
To be able to identify, model and produce solutions against to problems related to molecular biology and genetics
PO-3
To start a procedure, proceed and finalize about determined problem by using analytical techniques
PO-4
To be able to understand all knowledge about living organisms which is main subject of molecular biology and genetics
PO-5
To contribute scientific research and development and add further information
PO-6
To be able to analyze data, design an experiment and proceed and annoate the results
PO-7
To be able to use current techniques and analysis methods in molecular biology and genetics
PO-8
To be able to be a part of a team in disciplinary or multidisciplinary, national or international public problems focused projects and use at least one foreign language for vocational purposes
PO-9
To be able to behave individually, take initiative and creativity skills
PO-10
To communicate briefly and clear using oral or written presentation skills to present individual working performance and independent decisions
PO-11
To carry responsibility to vocational and ethical issues
PO-12
To be aware about quality assessment
PO-13
To adopt in principle the importance of life-learning subject and graduate self-development by following new literature about field and apply current knowledge
Learning Outcomes
LO-1
To be able to define stem cell term and analyze various types of stem cells according to their pluripotential characteristics
LO-2
To be able to compare embryonic and adult stem cells
LO-3
To distinguish stem cell sources in the body
LO-4
To have knowledge about high throughput techiques for isolation and characterization of stem cells.
LO-5
To know ethical and legal regulations for stem cell based therapies and to be able to discuss their potential therapeutic aspects
