Major classes of enzymes will be introduced. Structure-function relationship will be studied. The strategies which can be used for purification, catalysis and regulation will be covered. Applications that are based on a broad use of enzymes will also be discussed.
Prerequisite(s)
Course Code Course Name…
Corequisite(s)
Course Code Course Name…
Special Requisite(s)
Biochemistry 1 (MBG501) provides the necessary background for the course and will help if taken.
-Lecture, discussion and visual aids (films and internet applications)
Principle Sources
-Fundamentals of enzymology, N.C. Price and L. Stevens, OUP, 3rd edition
Other Sources
-Recent papers related with course material
Course Schedules
Week
Contents
Learning Methods
1. Week
Introduction to enzymology
Oral presentation, case study
2. Week
Purification of enzymes 1
Oral presentation, case study
3. Week
Purification of enzymes 2
Oral presentation, case study
4. Week
Purification of enzymes 3
Oral presentation, case study
5. Week
Structure of enzymes 1
Oral presentation, case study
6. Week
Structure of enzymes 2
Oral presentation, case study
7. Week
Structure of enzymes 3
Oral presentation, case study
8. Week
Introduction to enzyme kinetics 1
Oral presentation, case study
9. Week
Introduction to enzyme kinetics 2
Oral presentation, case study
10. Week
Enzyme mechanisms1
Oral presentation, case study
11. Week
Enzyme mechanisms 2
Oral presentation, case study
12. Week
Enzyme mechanisms 3
Oral presentation, case study
13. Week
Turnover of enzymes 1
Oral presentation, case study
14. Week
Turnover of enzymes 2
Oral presentation, case study
15. Week
16. Week
17. Week
Assessments
Evaluation tools
Quantity
Weight(%)
Midterm(s)
1
15
Homework / Term Projects / Presentations
1
35
Final Exam
1
50
Program Outcomes
PO-1
To apply all knowledge about basic sciences such as mathematics, physics, chemistry and biology to all problems in molecular biology and genetics
PO-2
To be able to identify, model and produce solutions against to problems related to molecular biology and genetics
PO-3
To start a procedure, proceed and finalize about determined problem by using analytical techniques
PO-4
To be able to understand all knowledge about living organisms which is main subject of molecular biology and genetics
PO-5
To contribute scientific research and development and add further information
PO-6
To be able to analyze data, design an experiment and proceed and annoate the results
PO-7
To be able to use current techniques and analysis methods in molecular biology and genetics
PO-8
To be able to be a part of a team in disciplinary or multidisciplinary, national or international public problems focused projects and use at least one foreign language for vocational purposes
PO-9
To be able to behave individually, take initiative and creativity skills
PO-10
To communicate briefly and clear using oral or written presentation skills to present individual working performance and independent decisions
PO-11
To carry responsibility to vocational and ethical issues
PO-12
To be aware about quality assessment
PO-13
To adopt in principle the importance of life-learning subject and graduate self-development by following new literature about field and apply current knowledge
Learning Outcomes
LO-1
To be able to purify, characterize, study catalytic activity of any enzyme from desired organism
LO-2
To be able to design and produce mutant enzymes/ proteins
LO-3
To be able to design in vivo and in vitro assays for any enzyme
LO-4
To be able to study enzyme turnover
LO-5
To be able design novel inhibitors or susbtrate analogs for enzymes
