To describe the human genetics and it's terms, teaching the molecular mechanism of monogenic, polygenic, chromosomal and mitochondrial hereditary genetic diseases by using the OMIM data base and scientific papers, give information about the immunogenetics, pharmacogenetics
Prerequisite(s)
-
Corequisite(s)
-
Special Requisite(s)
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Instructor(s)
Professor Seyhan Altun
Course Assistant(s)
-
Schedule
Monday; 13:00-15:00
Office Hour(s)
Assoc. Prof. Ajda Çoker Gürkan, Friday; 11:00-12:00, Ataköy Campüs, AK/M-Z-09
Teaching Methods and Techniques
- Powerpoint presentations of courses
-Reading and discussing papers related to course subject.
- Video demonstrations linked to couse subject
Principle Sources
-Human Genetics: Concepts and Applications, R Lewis, 9. Edition, McGraw-Hill Science/Engineering/Math, 2009.
-Human Genetics and Genomics, BR. Korf, 3. Edition, Wiley-Blackwel, 2006.
- Thompson & Thompson Genetics in Medicine, R Nussbaum, RR. McInnes, HF Willard, 7 edition, Saunders, 2007.
- An Introduction to Human Molecular Genetics: Mechanisms of Inherited Diseases, JJ. Pasternak, 2 edition,Wiley-Liss, 2005.
- A Guide to Genetic Counseling, WR Uhlmann, JL Schuette, B Yashar, 2 edition, Wiley-Blackwell, 2009.
- A Guide to Human Gene Therapy, RW Herzog, S Zolotukhin, 1. Edition, Springer, 2010.
Other Sources
-www.sciencedirect.com
-www.ncb.nlm.nih.gov.tr
Course Schedules
Week
Contents
Learning Methods
1. Week
Introduction to Human Genetics and brief information about human genetics application fields
Oral presentation, discussion, demonstration
2. Week
Molecular mechanism of rare autosomal monogenic diseases
Oral presentation, discussion, demonstration
3. Week
Molecular mechanism of rare X-linked monogenic diseases
Oral presentation, discussion, demonstration
4. Week
Non-Mendelian Genetics Hereditary and Polygenic hereditary and polygenic genetic diseases and characteristics
To apply all knowledge about basic sciences such as mathematics, physics, chemistry and biology to all problems in molecular biology and genetics
PO-2
To be able to identify, model and produce solutions against to problems related to molecular biology and genetics
PO-3
To start a procedure, proceed and finalize about determined problem by using analytical techniques
PO-4
To be able to understand all knowledge about living organisms which is main subject of molecular biology and genetics
PO-5
To contribute scientific research and development and add further information
PO-6
To be able to analyze data, design an experiment and proceed and annoate the results
PO-7
To be able to use current techniques and analysis methods in molecular biology and genetics
PO-8
To be able to be a part of a team in disciplinary or multidisciplinary, national or international public problems focused projects and use at least one foreign language for vocational purposes
PO-9
To be able to behave individually, take initiative and creativity skills
PO-10
To communicate briefly and clear using oral or written presentation skills to present individual working performance and independent decisions
PO-11
To carry responsibility to vocational and ethical issues
PO-12
To be aware about quality assessment
PO-13
To adopt in principle the importance of life-learning subject and graduate self-development by following new literature about field and apply current knowledge
Learning Outcomes
LO-1
Can describe the Human genetics and discriminate the genetic variations types
LO-2
Can notice the difference between molecular mechanism of Mendelian type hereditary genetic diseases and polygenic hereditary genetic diseases.
LO-3
Can comprehend the hereditary of genetic diseases by using the genetic knowledge
LO-4
Can figure out the molecular mechanism of hereditary genetic diseases by using the knowledge about advanced molecular biological methods.
LO-5
Can investigate the molecular backgorund immunogenetic, developmental genetics and behavioural genetics by comprehending the molecular mechanisim of the disease etiology
LO-6
Can comprehend the application and essential role of human genetics in public health and by assimilating the gene therapy methods and create new ideas in this field
LO-7
Can use the OMIM data base about the human genetic disease and can get knowledge by finding the scientific papers, present and discuss about the subject
