To give information about In vitro fertilization (IVF) and preimplantational genetic diagnosis (PGD) terms, steps of IVF, laboratory conditions and techniques, and also to teach the how to diagnose the monogenic and chromosomal disorders and to give information about the future of PGD
Prerequisite(s)
-
Corequisite(s)
-
Special Requisite(s)
Genetics and human genetics courses
Instructor(s)
Assist. Prof. Dr. Burcu Ayhan Şahin
Course Assistant(s)
-
Schedule
Friday; 9:00-11:00
Office Hour(s)
Assoc. Prof. Ajda Çoker Gürkan, Friday; 11:00-12:00, Atakoy Campüs, AK/M-Z-09
Teaching Methods and Techniques
- Powerpoint presentations of courses
-Reading and discussing papers related to course subject.
- Video demonstrations linked to couse subject
Principle Sources
-In Vitro Fertilization: A Practical Approach, DK. Gardner, 3. Edition, Informa Healthcare, 2006.
-In vitro fertilizastion, K. Elder, B. Dale, Y. Menezo, J. Harper, 3. Edition, Cambridge University Press, 2011.
Prenatal Diagnosis: Cases and Clinical Challenges, MS. Dimaio, JE. Fox, MJ. Mahoney, 1. Edition, Wiley-Blackwell, 2010.
-Genetic Disorders and the Fetus: Diagnosis, Prevention and Treatment, A. Milunsky, J. Milunsky,
Edition, The Johns Hopkins University Press, 2010.
-Preimplantation Genetic Diagnosis, J. Harper, 2. Edition, Cambridge University Press, 2009.
Other Sources
-www.sciencedirect.com
-www.ncb.nlm.nih.gov
Course Schedules
Week
Contents
Learning Methods
1. Week
Introduction to preimplantational genetic diagnosis and in vitro fertilization (IVF)
- Oral presentation, discussion, demonstration
2. Week
Semen analysis and preperation of sperm for IVF
- Oral presentation, discussion, demonstration
3. Week
Preperation of oosit for IVF
- Oral presentation, discussion, demonstration
4. Week
In vitro fertilization and analysis of fertilization
- Oral presentation, discussion, demonstration
5. Week
Embriyo culture systems and Embryo transfer techniques, Oocyte and embriyo cryopreservation
- Oral presentation, discussion, demonstration
6. Week
Biopsy techniques, Amniocentesis and coryonic villus sampling
- Oral presentation, discussion, demonstration
7. Week
Midterm exam
- Oral presentation, discussion, demonstration
8. Week
Preimplantation genetic diagnosis (PGd) and PGD analysis
- Oral presentation, discussion, demonstration
9. Week
PGD and monogenetic disorders (discussion of the scientific paper link to subject)
- Oral presentation, discussion, demonstration
10. Week
PDG and HLA typing (discussion of the scientific paper link to subject)
- Oral presentation, discussion, demonstration
11. Week
Prenatal diagnosis of chromosomal arrangement abnormalities and discussion of the scientific paper link to subject
To apply all knowledge about basic sciences such as mathematics, physics, chemistry and biology to all problems in molecular biology and genetics
PO-2
To be able to identify, model and produce solutions against to problems related to molecular biology and genetics
PO-3
To start a procedure, proceed and finalize about determined problem by using analytical techniques
PO-4
To be able to understand all knowledge about living organisms which is main subject of molecular biology and genetics
PO-5
To contribute scientific research and development and add further information
PO-6
To be able to analyze data, design an experiment and proceed and annoate the results
PO-7
To be able to use current techniques and analysis methods in molecular biology and genetics
PO-8
To be able to be a part of a team in disciplinary or multidisciplinary, national or international public problems focused projects and use at least one foreign language for vocational purposes
PO-9
To be able to behave individually, take initiative and creativity skills
PO-10
To communicate briefly and clear using oral or written presentation skills to present individual working performance and independent decisions
PO-11
To carry responsibility to vocational and ethical issues
PO-12
To be aware about quality assessment
PO-13
To adopt in principle the importance of life-learning subject and graduate self-development by following new literature about field and apply current knowledge
Learning Outcomes
LO-1
Can decide the appropriate method in PDG analysis according to molecular mechanism of the genetic disorders by using the knowledge in human genetics
LO-2
Can discriminate the molecular mechanism and hereditary of the genetic diseases that are diagnosed according to PGD analysis by using the advanced molecular biology methods
LO-3
Can use the OMIM database to get information about the genetic human diseases, can find correct scientific paper about the subject and can present and also discuss.
LO-4
Can have informaiton about the term of In vitro fertilization (IVF) and it's steps
LO-5
Can comprehend the IVF laboratory conditions, the equipments used in IVF laboratory and the techniques
LO-6
Can gain information about the terms of Preimplantation genetic diagnosis and it's aim
