Course Code	Semester	Course Name	LE/RC/LA	Course Type	Language of Instruction	ECTS
MBG6012		Molecular Endocrinology	2/0/0	DE	Turkish	4

Course Goals	The aim of the course is to demonstrate the molecular mechanism of hormone deficiency and understand the biological functions of endocrine gland or metabolic mediated hormones, signaling pathway, classical and non-classical endocrine dependent hormon and receptor types.
Prerequisite(s)
Corequisite(s)
Special Requisite(s)
Instructor(s)	Assist. Prof. Dr. Özge Rencüzoğulları
Course Assistant(s)
Schedule
Office Hour(s)
Teaching Methods and Techniques	- Powerpoint demonstration - Lecture related scientific papers  - Video presentations
Principle Sources	- Molecular Endocrinology, Franklyn F. Bolander, Third Edition, Elsevier Academic Press. - Basic Medical Endocrinology, Fourth Edition
Other Sources	www.ncbi.nlm.nih.gov www.sciencedirect.com

Course Schedules
Week	Contents	Learning Methods
1. Week	Introduction to molecular endocrinology and brief information about application fields	Powepoint, video demonstation and scientific paper discussion
2. Week	Classical and non-classical endocrinology	Powepoint, video demonstation and scientific paper discussion
3. Week	Hormone and receptor types, Hormone signaling: seconder mesangers	Powepoint, video demonstation and scientific paper discussion
4. Week	Pituitary gland hormone and molecular mechanism of pituitary gland hormone deficient diseases	Powepoint, video demonstation and scientific paper discussion
5. Week	Tyroid gland hormone and molecular mechanism of tyroid gland hormone deficient diseases	Powepoint, video demonstation and scientific paper discussion
6. Week	Adrenale gland hormone and molecular mechanism of adrenale gland hormone deficient diseases	Powepoint, video demonstation and scientific paper discussion
7. Week	Midterm	Analysis, discussion
8. Week	Gastrointestinal tract hormone and molecular mechanism of gastrointestinal tract hormone deficient diseases	Powepoint, video demonstation and scientific paper discussion
9. Week	Molecular mechanism of reproductive system hormone	Powepoint, video demonstation and scientific paper discussion
10. Week	Actual scientific paper reading and discussion	Powepoint, video demonstation and scientific paper discussion
11. Week	Actual scientific paper reading and discussion	Powepoint, video demonstation and scientific paper discussion
12. Week	Actual scientific paper reading and discussion	Powepoint, video demonstation and scientific paper discussion
13. Week	Actual scientific paper reading and discussion	Powepoint, video demonstation and scientific paper discussion
14. Week	Actual scientific paper reading and discussion	Powepoint, video demonstation and scientific paper discussion
15. Week	Final exam	Analysis, discussion
16. Week	Final exam	Analysis, discussion
17. Week	Final exam	Analysis, discussion

Assessments
Evaluation tools	Quantity	Weight(%)
Midterm(s)	1	30
Homework / Term Projects / Presentations	1	15
Attendance	1	10
Final Exam	1	45

Program Outcomes PO-1 To apply all knowledge about basic sciences such as mathematics, physics, chemistry and biology to all problems in molecular biology and genetics PO-2 To be able to identify, model and produce solutions against to problems related to molecular biology and genetics PO-3 To start a procedure, proceed and finalize about determined problem by using analytical techniques PO-4 To be able to understand all knowledge about living organisms which is main subject of molecular biology and genetics PO-5 To contribute scientific research and development and add further information PO-6 To be able to analyze data, design an experiment and proceed and annoate the results PO-7 To be able to use current techniques and analysis methods in molecular biology and genetics PO-8 To be able to be a part of a team in disciplinary or multidisciplinary, national or international public problems focused projects and use at least one foreign language for vocational purposes PO-9 To be able to behave individually, take initiative and creativity skills PO-10 To communicate briefly and clear using oral or written presentation skills to present individual working performance and independent decisions PO-11 To carry responsibility to vocational and ethical issues PO-12 To be aware about quality assessment PO-13 To adopt in principle the importance of life-learning subject and graduate self-development by following new literature about field and apply current knowledge

Learning Outcomes LO-1 To undestand the classical and non-classical endocrinology LO-2 To discriminate the structural and genetic dependent hormone and receptor types LO-3 To understand the molecular mechanism of hormone receptor signaling LO-4 To learn molecular mechanism of endocrine system dependent deficient diseses LO-5 To undestand the principles of advanced molecular methods to determine the endocrine deficiency

Course Assessment Matrix:

PO 1

PO 2

PO 3

PO 4

PO 5

PO 6

PO 7

PO 8

PO 9

PO 10

PO 11

PO 12

PO 13