In industrial scale seconder metabolyte production, strategies, metabolic pathways, regulations, plant and microbial-based seconder metabolyte productions and applications and biotechnological processes
Prerequisite(s)
-
Corequisite(s)
-
Special Requisite(s)
-
Instructor(s)
Professor Seyhan Altun
Course Assistant(s)
Schedule
Friday 10.00-12.00
100% distance learning via CATS platform
Office Hour(s)
Ataköy Campus
Online meetings via CATS platform
Teaching Methods and Techniques
Oral and ppt presentations
Principle Sources
1. Plant secondary metabolites: Dynamical regulation in response to environmental factors, 2017 by Tiago Olivoto, Maicon Nardino and Velci Queiróz de Souza
2. Transgenesis and Secondary Metabolism (Reference Series in Phytochemistry), 2017 by Sumita Jha
3. Extremophilic Cyanobacteria For Novel Drug Development (SpringerBriefs in Pharmaceutical Science & Drug Development) 2014 by Sikha Mandal and Jnanendra Rath
4. Functions and Biotechnology of Plant Secondary Metabolites, Second Edition, Blackwell Publishing Ltd, 2010 by M. Wink
5. Biotechnology: Products of Secondary Metabolism, Volume 7, Second Edition, Wiley Company, 2008 by H.J. Rehm, G. Reed
Other Sources
Course Schedules
Week
Contents
Learning Methods
1. Week
Introduction to secondary metabolism, the importance of seconder metabolytes as pharmaceuticals, the regulations of seconder metabolyte production
Oral and ppt presentation
2. Week
Antibacterial, antifungal and antiviral effects of seconder metabolytes
Oral and ppt presentation
3. Week
Plant-based seconder metabolytes, new medicinal applications of plant-based secondary metabolytes
Oral and ppt presentation
4. Week
Plant based seconder metabolytes, the importance of plant cell cultures
Oral and ppt presentation
5. Week
Biosynthesis of seconder metabolytes
Oral and ppt presentation
6. Week
Antibiotics, regulation of bacterial antibiotic production, β-Laktam, peptide, glicopeptide and policetide antibiotics
Oral and ppt presentation
7. Week
Midterm exam
Exam
8. Week
Phenols, polyphenols and tanins
Oral and ppt presentation
9. Week
Sulphur based components, terpens, alcaloids, acetylens, falvanoids
Production of seconder metabolytes, technological approaches
Oral and ppt presentation
12. Week
Production of seconder metabolytes, technological approaches
Oral and ppt presentation
13. Week
Recent literature search about the issue
Oral and ppt presentation
14. Week
Recent literature search about the issue/ Project presentations
Oral and ppt presentation
15. Week
Project presentations
Oral and ppt presentation
16. Week
Final exam
Exam
17. Week
Final exam
Exam
Assessments
Evaluation tools
Quantity
Weight(%)
Midterm(s)
1
10
Homework / Term Projects / Presentations
1
20
Project(s)
1
20
Attendance
1
10
Final Exam
1
40
Program Outcomes
PO-1
To apply all knowledge about basic sciences such as mathematics, physics, chemistry and biology to all problems in molecular biology and genetics
PO-2
To be able to identify, model and produce solutions against to problems related to molecular biology and genetics
PO-3
To start a procedure, proceed and finalize about determined problem by using analytical techniques
PO-4
To be able to understand all knowledge about living organisms which is main subject of molecular biology and genetics
PO-5
To contribute scientific research and development and add further information
PO-6
To be able to analyze data, design an experiment and proceed and annoate the results
PO-7
To be able to use current techniques and analysis methods in molecular biology and genetics
PO-8
To be able to be a part of a team in disciplinary or multidisciplinary, national or international public problems focused projects and use at least one foreign language for vocational purposes
PO-9
To be able to behave individually, take initiative and creativity skills
PO-10
To communicate briefly and clear using oral or written presentation skills to present individual working performance and independent decisions
PO-11
To carry responsibility to vocational and ethical issues
PO-12
To be aware about quality assessment
PO-13
To adopt in principle the importance of life-learning subject and graduate self-development by following new literature about field and apply current knowledge
Learning Outcomes
LO-1
To have knowledge about plant-based seconder metabolytes
LO-2
To have knowledge about the types of microorganisms based bioactive seconder metabolytes
LO-3
To understand the importance of seconder metabolytes in pharmaceutical industry
LO-4
To learn the metabolic pathways related with seconder metabolytes and their regulatory mechanisms
LO-5
To have the knowledge about the technological applications in seconder metabolyte productions
