Learning metabolic synthesis of nucleic acids, purine and pyrimidine nucleotides and deoxyribonucleotides, understanding inhibitors of nucleic acid synthesis and special regulation mechanisms, understanding the importance of nucleic acid biosynthesis, learning the synthesis of special regulation mechanisms, understanding nucleotide catabolism and its importance in cellular mechanism
Prerequisite(s)
-
Corequisite(s)
-
Special Requisite(s)
-
Instructor(s)
Assist. Prof. Dr. Pelin Özfiliz Kılbaş
Course Assistant(s)
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Schedule
Friday, 10:00-13:00, MOBIGEN
Office Hour(s)
Weekdays, Molecular Biology and Genetics Department,
Teaching Methods and Techniques
- Powerpoint presentation
- Lecture
- Discussion
- Independent study
- Animation and videos
- Internet research
- Reading and discussion of scientific publicaitons
Principle Sources
- Genes IX, 9th Edition, by Benjamin Lewin, ISBN-13: 978-0763740634
- Lehninger Principles of Biochemistry, 6th Edition, by David L. Nelson, ISBN-13: 978-1429234146
- Molecular Biology of RNA, 1st Edition, by David Elliot, ISBN-13: 978-0199288373
Other Sources
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Course Schedules
Week
Contents
Learning Methods
1. Week
Introduction to nucleic acid biochemistry, basic terms and definitions used
-powerpoint presentation and scientific article review
2. Week
Structure of nucleotides, nucleic acids, DNA and RNA
-powerpoint presentation and scientific article review
3. Week
DNA metabolism
-powerpoint presentation and scientific article review
4. Week
RNA metabolism
-powerpoint presentation and scientific article review
5. Week
Synthesis and catabolism of purine nucleotides
-powerpoint presentation and scientific article review
6. Week
Synthesis and catabolism of pyrimidine nucleotides
-powerpoint presentation and scientific article review
7. Week
midterm exam
8. Week
Destruction of nucleic acids and nucleotides
-powerpoint presentation and scientific article review
9. Week
Purification methods of nucleic acids
-powerpoint presentation and scientific article review
10. Week
Nucleotide and nucleic acid metabolism diseases
-powerpoint presentation and scientific article review
11. Week
Methods used to elucidate the structure and mechanism of nucleic acids
-powerpoint presentation and scientific article review
12. Week
Current issues and applications in nucleic acid biochemistry
-powerpoint presentation and scientific article review
13. Week
Current issues and applications in nucleic acid biochemistry
-powerpoint presentation and scientific article review
14. Week
15. Week
16. Week
17. Week
Assessments
Evaluation tools
Quantity
Weight(%)
Midterm(s)
1
30
Homework / Term Projects / Presentations
1
30
Final Exam
1
40
Program Outcomes
PO-1
To be able to determine the field related problems and analysis them to find the solutions as a specialist by using the knowledge coming from undergraduate level.
PO-2
To be able to develop and apply research strategies, which depend on the new technological achievements, for novel studies about molecular cell biology, plant biotechnology and molecular genetics fields on the basis of undergraduate qualifications.
PO-3
To be able to discuss field related subjects by using at least one foreign language.
PO-4
To be sensitive against public problems and be able to create solutions to these problems by synthesis of knowledge coming from other disciplines with the abilities and knowledge of the related field
PO-5
To be able to take independent decision in the frame of specialized knowledge and scientific approach about field and lead/proceed a project by using creativity skills.
PO-6
To be able to decide independently during solving the problem and contribute the group labor in harmony.
PO-7
To be able to present information which is supported by quantitative and qualitative data to groups in/outside of the field by written, oral and visually.
PO-8
To consider to behave properly in human rights and scientific ethics at research.
PO-9
To be able to use informatics and communication skills according required level for area.
PO-10
To obtain required quality about field in order to maintain higher academic degree
Learning Outcomes
LO-1
Ability to use background information on molecular biology to understand nucleotide biosynthesis and regulation.
LO-2
Comprehension of role and importance of nucleotide biosynthesis and catabolism in cellular metabolism.
LO-3
Understanding tertiary structure of nucleotides and its importance in regulation of metabolism.
LO-4
Gaining ability to examination and interpretation of recent scientific publications on nucleotide biosynthesis and catabolism.
LO-5
Ability to use information gained during education for understanding scientific knowledge and prediction of solutions for social problems.
